Target Information
Target General Infomation | |||||
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Target ID |
T85223
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Former ID |
TTDR00828
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Target Name |
Deoxyribonuclease I
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Gene Name |
DNASE1
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Synonyms |
Alkaline deoxyribonuclease; DNase I; Dornase alfa; Herpesvirus alkaline DNase; Herpesvirus alkaline deoxyribonuclease; DNASE1
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Target Type |
Research
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Function |
Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity).
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BioChemical Class |
Endodeoxyribonucleases
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UniProt ID | |||||
EC Number |
EC 3.1.21.1
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Sequence |
MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
EVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYD DGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKW GLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAG MLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK |
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References |
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