Target Information
Target General Infomation | |||||
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Target ID |
T67754
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Former ID |
TTDR00094
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Target Name |
Transketolase
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Gene Name |
TKT
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Synonyms |
TK; TKT
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Target Type |
Research
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Function |
Catalyzes the transfer ofa two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
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BioChemical Class |
Transferases of aldehyde or ketone residues
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UniProt ID | |||||
EC Number |
EC 2.2.1.1
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Sequence |
MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS
QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE LLKMFGIDRDAIAQAVRGLITKA |
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Pathways | |||||
BioCyc Pathway | Pentose phosphate pathway | ||||
Pentose phosphate pathway (non-oxidative branch) | |||||
KEGG Pathway | Pentose phosphate pathway | ||||
Metabolic pathways | |||||
Biosynthesis of antibiotics | |||||
Carbon metabolism | |||||
Biosynthesis of amino acids | |||||
PANTHER Pathway | Pentose phosphate pathway | ||||
PathWhiz Pathway | Pentose Phosphate Pathway | ||||
Warburg Effect | |||||
WikiPathways | Metabolism of carbohydrates | ||||
Integration of energy metabolism | |||||
Pentose Phosphate Pathway | |||||
References |
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