Drug General Information
Drug ID
D0OD8N
Former ID
DNC002781
Drug Name
1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL

Formula
C8H18O4
Canonical SMILES
COCCOCCOCCOC
InChI
1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3
InChIKey
YFNKIDBQEZZDLK-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Transketolase Target Info Inhibitor [551393]
Fyn tyrosine kinase Target Info Inhibitor [551393]
BioCyc Pathway Pentose phosphate pathway
Pentose phosphate pathway (non-oxidative branch)
KEGG Pathway Pentose phosphate pathway
Metabolic pathways
Biosynthesis of antibiotics
Carbon metabolism
Biosynthesis of amino acidshsa04071:Sphingolipid signaling pathway
Axon guidance
Osteoclast differentiation
Focal adhesion
Adherens junction
Platelet activation
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Cholinergic synapse
Prion diseases
Pathogenic Escherichia coli infection
Measles
Viral myocarditis
NetPath Pathway TSH Signaling Pathway
IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Pentose phosphate pathwayP00007:Axon guidance mediated by semaphorins
Cadherin signaling pathway
Integrin signalling pathway
Parkinson disease
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
ErbB4 signaling events
Glypican 1 network
TCR signaling in na&#xef
Signaling events mediated by PTP1B
Ephrin A reverse signaling
Reelin signaling pathway
Regulation of p38-alpha and p38-beta
TCR signaling in na&#xef
Angiopoietin receptor Tie2-mediated signaling
Thromboxane A2 receptor signaling
Netrin-mediated signaling events
IL2-mediated signaling events
CXCR4-mediated signaling events
Class I PI3K signaling events
Posttranslational regulation of adherens junction stability and dissassembly
amb2 Integrin signaling
EPHA forward signaling
E-cadherin signaling in keratinocytes
PDGFR-beta signaling pathway
Nephrin/Neph1 signaling in the kidney podocyte
Signaling events mediated by VEGFR1 and VEGFR2
Syndecan-3-mediated signaling events
Ephrin B reverse signaling
Alpha-synuclein signaling
Signaling events mediated by focal adhesion kinase
PathWhiz Pathway Pentose Phosphate Pathway
Warburg EffectPW000453:Fc Epsilon Receptor I Signaling in Mast Cells
Reactome GPVI-mediated activation cascade
PIP3 activates AKT signaling
Regulation of KIT signaling
Cell surface interactions at the vascular wall
FCGR activation
PECAM1 interactions
Constitutive Signaling by Aberrant PI3K in Cancer
DAP12 signaling
EPH-Ephrin signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Nephrin interactions
NCAM signaling for neurite out-growth
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
CD28 dependent Vav1 pathway
CTLA4 inhibitory signaling
EPHB-mediated forward signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells
CRMPs in Sema3A signaling
DCC mediated attractive signaling
Netrin mediated repulsion signals
VEGFA-VEGFR2 Pathway
Dectin-2 family
CD209 (DC-SIGN) signaling
RAF/MAP kinase cascade
Platelet Adhesion to exposed collagen
Regulation of signaling by CBL
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways Metabolism of carbohydrates
Integration of energy metabolism
Pentose Phosphate PathwayWP69:TCR Signaling Pathway
Interferon type I signaling pathways
IL-2 Signaling Pathway
Kit receptor signaling pathway
IL-3 Signaling Pathway
Ectoderm Differentiation
Fc epsilon receptor (FCERI) signaling
Signaling by the B Cell Receptor (BCR)
Signaling by SCF-KIT
DAP12 interactions
Host Interactions of HIV factors
PIP3 activates AKT signaling
T-Cell Receptor and Co-stimulatory Signaling
Primary Focal Segmental Glomerulosclerosis FSGS
BDNF signaling pathway
Interleukin-11 Signaling Pathway
B Cell Receptor Signaling Pathway
Pathogenic Escherichia coli infection
TSLP Signaling Pathway
IL-7 Signaling Pathway
Leptin signaling pathway
Semaphorin interactions
Platelet Adhesion to exposed collagen
Netrin-1 signaling
Nephrin interactions
NCAM signaling for neurite out-growth
Integrin-mediated Cell Adhesion
GPVI-mediated activation cascade
Costimulation by the CD28 family
Cell surface interactions at the vascular wall
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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