| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T20669 | ||||
| Target Name | mRNA of PKA Catalytic Subunit C-alpha | ||||
| Target Type | Discontinued |
||||
| Drug Potency against Target | NM-PP1 | Drug Info | IC50 = 500 nM | [529039] | |
| BALANOL | Drug Info | Ki = 4.7 nM | [527710] | ||
| Ro-4396686 | Drug Info | IC50 = 9010 nM | [528018] | ||
| References | |||||
| Ref 529039 | Biochem J. 2007 Dec 15;408(3):297-315.The selectivity of protein kinase inhibitors: a further update. | ||||
| Ref 527710 | J Med Chem. 2005 Sep 8;48(18):5613-38.Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. | ||||
| Ref 528018 | Bioorg Med Chem Lett. 2006 Apr 1;16(7):1950-3. Epub 2006 Feb 3.Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. | ||||
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