| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T41515 | ||||
| Target Name | mRNA of FGFR4 | ||||
| Target Type | Research |
||||
| Drug Potency against Target | Ro-4396686 | Drug Info | IC50 = 92 nM | [528018] | |
| PD-0183812 | Drug Info | IC50 = 8620 nM | [525924] | ||
| References | |||||
| Ref 528018 | Bioorg Med Chem Lett. 2006 Apr 1;16(7):1950-3. Epub 2006 Feb 3.Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. | ||||
| Ref 525924 | J Med Chem. 2000 Nov 30;43(24):4606-16.Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases. | ||||
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