Drug Information

Drug General Information
Drug ID
D0GX3L
Former ID
DNCL003540
Drug Name
Arbaclofen placarbil
Synonyms
AP; R-baclofen - XenoPort; XP-19986
Drug Type
Small molecular drug
Indication Fragile X syndrome [ICD9: 332, 759.83; ICD10:F02.3, G20, Q99.2] Phase 3 [523413]
Company
Genentech
Structure
Download
2D MOL

3D MOL
Formula
C19H26ClNO6
Canonical SMILES
C1=CC(=CC=C1C(CC(=O)O)CN)Cl
InChI
1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1
InChIKey
KPYSYYIEGFHWSV-QMMMGPOBSA-N
PubChem Compound ID
11281011
PubChem Substance ID
3153571, 8178796, 11113710, 15121255, 15171983, 34709846, 50066102, 50705527, 90452213, 93625490, 103238751, 103941336, 104345301, 121277848, 123055284, 124490531, 124580859, 126581462, 126616647, 126685003, 126738367, 128418031, 134351756, 135249532, 135649977, 139309014, 143493644, 152032454, 152165673, 152238531, 152258754, 160647599, 160840514, 162009782, 162255234, 163099671, 163405182, 166222624, 170475242, 170485722, 172914818, 175266631, 175270364, 178100431, 186007019, 198993730, 204431203, 208265328, 223518884, 223679055
Target and Pathway
Target(s) GABA B receptor Target Info Modulator
References
Ref 523413ClinicalTrials.gov (NCT01325220) Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome. U.S. National Institutes of Health.

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