TTD | Drug: D0F4SN

Drug General Information
Drug ID	D0F4SN
Former ID	DIB002719
Drug Name	KUR-111
Synonyms	I-0401; I-040302; TGplPTH1-34; Fibrin-PTH (bone cysts), Kuros; Human parathyroid hormone (PTH) + TISSEEL fibrin sealant + hydroxyapatite/tri-calcium phosphate granules (bone fracture), Kuros/Baxter
Indication	Bone disease [ICD10:M00-M99]		Phase 2	[522008]
Company	Kuros Biosurgery AG
Target and Pathway
Target(s)	Parathyroid hormone ligand	Target Info	Modulator
Reactome	Class B/2 (Secretin family receptors)
Reactome	G alpha (s) signalling events
WikiPathways	Endochondral Ossification
	Osteoblast Signaling
	Vitamin D Receptor Pathway
	GPCR ligand binding
	GPCR downstream signaling
	Vitamin D Metabolism
References
Ref 522008	ClinicalTrials.gov (NCT00459641) Safety and Tolerability of I-040302 in Children and Young Adults With Solitary Bone Cysts. U.S. National Institutes of Health.

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Drug Information