Drug General Information
Drug ID
D0L5IA
Former ID
DIB016087
Drug Name
PEGylated hyaluronidase (human recombinant)
Synonyms
PEGylated hyaluronidase; PEGylated hyaluronidase (human recombinant) (intravenous, stroke/cancer), Halozyme
Indication Pancreatic cancer [ICD9: 140-199, 140-229, 157, 210-229; ICD10:C25] Phase 1/2 [525072]
Company
Halozyme Therapeutics San Diego; CA
Target and Pathway
Target(s) Hyaluronidase Target Info Modulator [544201]
References
Ref 525072ClinicalTrials.gov (NCT02346370) A Phase 1b/2, Study of Pegylated Recombinant Human Hyaluronidase Combined With Docetaxel Versus Docetaxel Alone in Subjects With Recurrent Previously Treated Locally Advanced or Metastatic NSCLC.. U.S. National Institutes of Health.
Ref 544201Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look. Cancer Discov. 2011 September; 1(4): 291-296.

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