Drug Information
Drug General Information | |||||
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Drug ID |
D05GBH
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Former ID |
DIB005848
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Drug Name |
F4co vaccine
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Synonyms |
F4co vaccine (AIDS/HIV infection)
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Drug Type |
Vaccine
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Company |
GlaxoSmithKline plc
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Target and Pathway | |||||
Target(s) | HIV p17 matrix protein | Target Info | [550167] | ||
HIV reverse transcriptase | Target Info | [550167] | |||
Negative factor | Target Info | [550167] | |||
HIV p24 capsid protein | Target Info | [550167] | |||
Reactome | Uncoating of the HIV Virion | ||||
Budding and maturation of HIV virion | |||||
Integration of provirus | |||||
Early Phase of HIV Life Cycle | |||||
Minus-strand DNA synthesis | |||||
Plus-strand DNA synthesis | |||||
2-LTR circle formation | |||||
Binding and entry of HIV virion | |||||
Membrane binding and targetting of GAG proteins | |||||
Assembly Of The HIV Virion | |||||
Integration of viral DNA into host genomic DNA | |||||
Autointegration results in viral DNA circles | |||||
APOBEC3G mediated resistance to HIV-1 infection | |||||
Vpr-mediated nuclear import of PICs | |||||
WikiPathways | Host Interactions of HIV factors | ||||
HIV Life Cycle | |||||
References | |||||
Ref 523204 | ClinicalTrials.gov (NCT01218113) Efficacy and Safety of GSK Biologicals HIV Vaccine in Antiretroviral Therapy (ART)-naive HIV-1 Infected Persons. U.S. National Institutes of Health. | ||||
Ref 548656 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027409) |
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