Drug Information

Drug General Information
Drug ID
D0D5ZR
Former ID
DIB009042
Drug Name
TRO-40303
Synonyms
Ischemia-reperfusion injury agent, Trophos; Neuroprotectant (motor neuron disease), Trophos
Indication Lateral sclerosis [ICD10:G12.2] Discontinued in Phase 2 [549216]
Company
Trophos SA
Structure
Download
2D MOL

3D MOL
Canonical SMILES
C(C[C@]1(/C(=N/O)/CC[C@@H]2[C@@H]1CC[C@]1([C@H]2CC[C@@H<br />]1[C@@H](CCCC(C)C)C)C)C)CO
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Modulator [544374]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 549216Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033814)
Ref 544374Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial. J Transl Med. 2014; 12: 38.

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