Drug Information

Drug General Information
Drug ID
D08QCJ
Former ID
DAP000664
Drug Name
Thiabendazole
Synonyms
Biogard; Bioguard; Bovizole; Cropasal; Drawipas; Eprofil; Equizole; Hymush; Lombristop; Mertec; Mertect; Mintesol; Mintezol; Mintezole; Minzolum; Mycozol; Nemacin; Nemapan; Omnizole; Ormogal; Pitrizet; Polival; RPH; Sistesan; Storite; Tbdz; Tebuzate; Tecto; Testo; Thiaben; Thiabendazol; Thiabendazolum; Thiabendole; Thiabenzazole; Thiabenzole; Thibendole; Thibenzol; Thibenzole; Thiprazole; Tiabenda; Tiabendazol; Tiabendazole; Tiabendazolum; Tobaz; Tresaderm; Triasox; Tubazole; Captan T; Equivet TZ; Equizole A; Helmindrax octelmin; Hokustar HP; Mertect lsp; RTU Flowable Fungicide; Tecto B; Tecto rph; Thibenzole att; Top Form Wormer; Chemviron TK 100; G 491; MK 360; Mertect 160; Mertect 340f; Metasol TK 100; Metasol tk 10; PS1057_SUPELCO; Sanaizol 100; Syntol M100; TBZ 6; TBZ 60W; Tecto 10P; Tecto 40F; Tecto 60; Thibenzole 200; Tibimix 20; APL-luster; Arbotect (TN); MK-360; Metasol TK-100; Mintezol (TN); TBZ-6; Thiabendazole (USP); Thiabendazole [BSI:ISO]; Thiabendazole [USAN:BAN]; Tiabendazolum [INN-Latin]; Tresaderm (TN); E-Z-Ex; Mintezol, Equizole, Thiabendazole; Tiabendazol [INN-Spanish, French]; Tiabendazole (JAN/INN); 2-(1,3-Thiazol-4-yl)-1H-benzimidazole; 2-(1,3-Thiazol-4-yl)benzimidazole; 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole; 2-(4'-Thiazolyl)benzimidazole; 2-(4-Thiazolyl)-1H-benzimidazole; 2-(4-Thiazolyl)benzimidazole; 2-(Thiazol-4-yl)benzimidazole; 2-Thiazol-4-yl-1H-benzoimidazole; 2-Thiazole-4-ylbenzimidazole; 2-[4-Thiazoly]benzimidazole; 4-(1H-benzimidazol-2-yl)-1,3-thiazole; 4-(2-Benzimidazolyl)thiazole
Drug Type
Small molecular drug
Indication Dutch elm disease; Helminth infection [ICD9: 001-139; ICD10:B81-B83, A00-B99] Approved [538473], [542326], [551871]
Therapeutic Class
Antinematodal Agents
Structure
Download
2D MOL

3D MOL
Formula
C10H7N3S
InChI
InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
InChIKey
WJCNZQLZVWNLKY-UHFFFAOYSA-N
CAS Number
CAS 148-79-8
PubChem Compound ID
5430
PubChem Substance ID
9341, 397296, 481912, 603021, 855607, 906414, 3319048, 4262837, 5643850, 7847438, 7868816, 7890801, 7980772, 8149550, 8153342, 10321759, 10508572, 10589481, 11112304, 11335247, 11360486, 11362813, 11365375, 11367937, 11372373, 11373926, 11376099, 11408671, 11446358, 11453179, 11461458, 11466552, 11467672, 11485217, 11486164, 11489147, 11491222, 11492169, 11493853, 11534461, 14717006, 15195537, 17389714, 24869246, 24899102, 24900297, 24900571, 26611942, 26679510, 26697097
ChEBI ID
ChEBI:45979
SuperDrug ATC ID
D01AC06; P02CA02
SuperDrug CAS ID
cas=000148798
Target and Pathway
Target(s) Fumarate reductase flavoprotein subunit Target Info Inhibitor [535056]
References
Ref 538473FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 016096.
Ref 542326(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7304).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535056Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87.

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