Drug Information

Drug General Information
Drug ID
D0S1OE
Former ID
DAP001252
Drug Name
Chlormezanone
Synonyms
Alinam; Banabin; Bisina; Chlomedinon; Chlormethazanone; Chlormethazone; Chlormezanon; Chlormezanona; Chlormezanonum; Clorilax; Clormetazanone; Clormetazon; Clormezanona; Clormezanone; Dichloromethazanone; Dichloromezanone; Lobak; Miorilax; Muskel; Myolespen; Phenarol; Rexan; Rilansyl; Rilaquil; Rilasol;Rilassol; Rilax; Rillasol; Supotran; Suprotan; Tanafol; Trancopal; Trancote; Tranrilax; Transanate; Clormezanone [DCIT]; WIN 4692; Banabil-sintyal; Banabin-sintyal; Banabin-syntyal; C-192; Chlormezanonum [INN-Latin]; Clormezanona [INN-Spanish]; Dl-Chlormezanone; Mio-sed; Muskel-Trancopal; TRANCOPAL (TN); Trancopal (TN); Chlormezanone (JAN/INN); Chlormezanone [BAN:INN:JAN]; Chlormezanone [INN:BAN:JAN]; (+-)-Chlormezanone; (+-)-Fenarol; 2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide; 2-(4-Chlorophenyl)-3-methyl-4-metathiazanone-1,1-dioxide; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H,1,3-thiazin-4-one 1,1-Dioxide; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide; 2-(4-Chlorphenyl)-3-methyl-4-metathiazanon-1,1-dioxid; 2-(4-chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one; 2-(p-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide; 2-(p-Chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide; 2-(para-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(4-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(4-chlorophenyl)tetrahydro-3-methyl-1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1,-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-1,1-dioxide; 4H-1,3-Thiazin-4-one, tetrahydro-2-(p-chlorophenyl)-3-methyl-, 1,1-dioxide
Drug Type
Small molecular drug
Indication Spasms; Pain; Anxiety disorder [ICD9: 338, 780, 300, 311; ICD10:R52, G89, F32, F40-F42] Approved [538447], [542346], [551871]
Therapeutic Class
Analgesics
Structure
Download
2D MOL

3D MOL
Formula
C11H12ClNO3S
InChI
InChI=1S/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3
InChIKey
WEQAYVWKMWHEJO-UHFFFAOYSA-N
CAS Number
CAS 80-77-3
PubChem Compound ID
2717
PubChem Substance ID
442083, 5050815, 7847334, 8150147, 8151758, 10321688, 10536330, 11336061, 11361300, 11363308, 11365870, 11368432, 11372047, 11374872, 11376594, 11462272, 11466364, 11467484, 11485529, 11486028, 11489623, 11490899, 11493051, 11494228, 14996956, 17404946, 26613160, 26679933, 26747112, 26751725, 28220405, 29221874, 46505352, 47291193, 47440324, 47440325, 47440326, 47736546, 47810809, 47885474, 48259297, 48259298, 48334563, 48334564, 48415758, 49698818, 50051463, 50104419, 50104420, 51023175
SuperDrug ATC ID
M03BB02
SuperDrug CAS ID
cas=000080773
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Agonist [537816]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 538447FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011467.
Ref 542346(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7323).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537816Successful treatment of anxiety with a single night-time dose of chlormezanone: double-blind comparison with diazepam. Curr Med Res Opin. 1982;8(1):33-8.

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