Drug Information

Drug General Information
Drug ID
D0Q4TK
Former ID
DAP001405
Drug Name
Morantel tartrate
Synonyms
Paratect; Banminth II; MORANTEL TARTRATE SALT; Morantel tartrate [USAN]; Morantel tartrate hydrate; CP 12009-18; Morantel tartrate (USP); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)-, (E)-, tartrate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)-, (E)-,tartrate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)ethenyl)-, (E)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)ethenyl)-, (E)-,(R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); (2R,3R)-2,3-dihydroxybutanedioic acid; (E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidine tartrate (1:1); 1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine; 2,3-dihydroxybutanedioic acid
Drug Type
Small molecular drug
Indication Mature gastrointestinal nematode infections [ICD9: 127; ICD10:B77-B81] Approved [551034]
Therapeutic Class
Anthelmintics
Structure
Download
2D MOL

3D MOL
Formula
C16H22N2O6S
Canonical SMILES
CC1=C(SC=C1)C=CC2=NCCCN2C.C(C(C(=O)O)O)(C(=O)O)O
InChI
1S/C12H16N2S.C4H6O6/c1-10-6-9-15-11(10)4-5-12-13-7-3-8-14(12)2;5-1(3(7)8)2(6)4(9)10/h4-6,9H,3,7-8H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/b5-4+;/t;1-,2-/m.1/s1
InChIKey
GGXQONWGCAQGNA-UUSVNAAPSA-N
CAS Number
CAS 26155-31-7
PubChem Compound ID
6433951
PubChem Substance ID
11620730, 43027499, 47206803, 50036532, 57367361, 79268307, 114544938, 134338613, 134998264, 137244464, 162226949, 175266306, 184580878, 226559313
Target and Pathway
Target(s) Fumarate reductase flavoprotein subunit Target Info Inhibitor [535056], [537845]
References
Ref 551034Morantel tartrate. Canadian Food Inspection Agency. Government of Canada. 2010-08.
Ref 535056Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87.
Ref 537845Fumarate reductase: a target for therapeutic intervention against Helicobacter pylori. Arch Biochem Biophys. 1995 Aug 1;321(1):153-9.

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