Drug General Information
Drug ID	D0Q6AD
Former ID	DNC010814
Drug Name	4'-(5-Chloro-2-thienyl)biphenyl-3-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530868]
Structure		Download 2D MOL 3D MOL
Formula	C16H11ClOS
Canonical SMILES	C1=CC(=CC(=C1)O)C2=CC=C(C=C2)C3=CC=C(S3)Cl
InChI	1S/C16H11ClOS/c17-16-9-8-15(19-16)12-6-4-11(5-7-12)13-2-1-3-14(18)10-13/h1-10,18H
InChIKey	ABAQWDXYFZGNGR-UHFFFAOYSA-N
PubChem Compound ID	46887551
Target and Pathway
Target(s)	Estradiol 17 beta-dehydrogenase 1	Target Info	Inhibitor	[530868]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	The canonical retinoid cycle in rods (twilight vision)
WikiPathways	Steroid Biosynthesis
	Metabolism of steroid hormones and vitamin D
	Prostate Cancer
References
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.

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