Drug Information

Drug General Information
Drug ID
D02JJX
Former ID
DIB021212
Drug Name
WAY-213613
Synonyms
WAY-213,613
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467767]
Structure
Download
2D MOL
Formula
C16H13BrF2N2O4
InChI
InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1
InChIKey
BNYDDAAZMBUFRG-ZDUSSCGKSA-N
PubChem Compound ID
11531745
PubChem Substance ID
16633786, 23657151, 42649774, 78862148, 124969480, 135698683, 136352761, 137010589, 162224466, 178101252, 241376055, 249617648, 252156685
Target and Pathway
Target(s) Excitatory amino acid transporter 2 Target Info Inhibitor [527637]
PANTHER Pathway Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
WikiPathways Amyotrophic lateral sclerosis (ALS)
References
Ref 467767(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4531).
Ref 527637Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2. Mol Pharmacol. 2005 Oct;68(4):974-82. Epub 2005 Jul 13.

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