Drug Information

Drug General Information
Drug ID
D0U7BJ
Former ID
DNC004246
Drug Name
2-[3-(4-Imidazol-1-yl-phenoxy)-propyl]-pyridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526913]
Structure
Download
2D MOL

3D MOL
Formula
C17H17N3O
Canonical SMILES
C1=CC=NC(=C1)CCCOC2=CC=C(C=C2)N3C=CN=C3
InChI
1S/C17H17N3O/c1-2-10-19-15(4-1)5-3-13-21-17-8-6-16(7-9-17)20-12-11-18-14-20/h1-2,4,6-12,14H,3,5,13H2
InChIKey
UGLPVHLKYTWQRV-UHFFFAOYSA-N
PubChem Compound ID
44341234
Target and Pathway
Target(s) Cytochrome P450 3A4 Target Info Inhibitor [526913]
Cytochrome P450 2D6 Target Info Inhibitor [526913]
KEGG Pathway Steroid hormone biosynthesis
Linoleic acid metabolism
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Bile secretion
Chemical carcinogenesishsa00980:Metabolism of xenobiotics by cytochrome P450
Serotonergic synapse
PathWhiz Pathway Caffeine Metabolism
Retinol Metabolism
Reactome Xenobiotics
Aflatoxin activation and detoxificationR-HSA-211981:Xenobiotics
WikiPathways Metapathway biotransformation
Aflatoxin B1 metabolism
Estrogen metabolism
Benzo(a)pyrene metabolism
Tamoxifen metabolism
Tryptophan metabolism
Oxidation by Cytochrome P450
Nuclear Receptors in Lipid Metabolism and Toxicity
Nuclear Receptors Meta-Pathway
Farnesoid X Receptor Pathway
Vitamin D Receptor Pathway
Felbamate Metabolism
Lidocaine metabolism
Nifedipine Activity
Colchicine Metabolic Pathway
Irinotecan Pathway
Drug Induction of Bile Acid Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine MetabolismWP702:Metapathway biotransformation
Aripiprazole Metabolic Pathway
Codeine and Morphine Metabolism
References
Ref 526913Bioorg Med Chem Lett. 2004 Jan 19;14(2):333-6.Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors.
Ref 526913Bioorg Med Chem Lett. 2004 Jan 19;14(2):333-6.Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors.

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