Drug Information

Drug General Information
Drug ID
D0C4OV
Former ID
DIB019266
Drug Name
compound 16a
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526911], [541566]
Structure
Download
2D MOL
Formula
C19H15N3O
InChI
InChI=1S/C19H15N3O/c1-23-18-12-14(8-9-15(18)16-6-2-4-10-20-16)17-13-22-11-5-3-7-19(22)21-17/h2-13H,1H3
InChIKey
DNCGFJANVDVZIZ-UHFFFAOYSA-N
PubChem Compound ID
10380127
PubChem Substance ID
15395026, 22734166, 34099742, 75847956, 139299995, 142902147, 178103043, 198951030, 223370077, 223975724, 231154857, 243371562
Target and Pathway
Target(s) Metabotropic glutamate receptor 5 Target Info Modulator (allosteric modulator) [526911]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Huntington's disease
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
Endogenous cannabinoid signaling
Reactome G alpha (q) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways Hypothetical Network for Drug Addiction
GPCRs, Class C Metabotropic glutamate, pheromone
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 526911Discovery of novel modulators of metabotropic glutamate receptor subtype-5. Bioorg Med Chem. 2004 Jan 2;12(1):17-21.
Ref 541566(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6427).
Ref 526911Discovery of novel modulators of metabotropic glutamate receptor subtype-5. Bioorg Med Chem. 2004 Jan 2;12(1):17-21.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.