Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B1PE
|
||||
| Former ID |
DNC001221
|
||||
| Drug Name |
Ro 5-4864
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Terminated | [545047] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H12Cl2N2O
|
||||
| Canonical SMILES |
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=C(C=C3)Cl
|
||||
| InChI |
1S/C16H12Cl2N2O/c1-20-14-7-6-12(18)8-13(14)16(19-9-15(20)21)10-2-4-11(17)5-3-10/h2-8H,9H2,1H3
|
||||
| InChIKey |
PUMYFTJOWAJIKF-UHFFFAOYSA-N
|
||||
| CAS Number |
CAS 72734-63-5
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
629453, 855615, 1064603, 5032806, 8151243, 15396253, 16961256, 24892765, 29220891, 47216957, 47291300, 47365397, 47589165, 47810947, 48035328, 48110640, 49845857, 49884088, 50100939, 56312857, 56422877, 57320986, 74938469, 89651644, 95515627, 103206184, 104298431, 109613651, 124799440, 124883503, 124883504, 128970145, 134223072, 134340266, 134340437, 134349213, 134990592, 137052431, 140280683, 162223583, 166729900, 178126525, 179046571, 198965137, 226442150, 250113435, 252340220
|
||||
| Target and Pathway | |||||
| Target(s) | Peripheral-type benzodiazepine receptor | Target Info | Binder | [535317], [538133] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| HTLV-I infection | |||||
| References | |||||
| Ref 535317 | Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells. Br J Cancer. 2001 Nov 30;85(11):1771-80. | ||||
| Ref 538133 | Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells. Biochem Pharmacol. 1998 Oct 15;56(8):1029-34. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.