Drug General Information |
Drug ID |
D09XZB
|
Former ID |
DAP000657
|
Drug Name |
Gefitinib
|
Synonyms |
Gefitini; IRE; Iressa; Irressat; Gefitinib [USAN]; ZD 1839; ZD1839; Iressa (TN); Iressa(TM); ZD-1839; CU-00000000396-1; Gefitinib,Iressa, ZD1839; Gefitinib (JAN/USAN/INN); ZD-1839, Iressa, Gefitinib; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine; N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine; 4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline; 6-(3-morpholinopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine; Tyrosine Kinase Inhibitor - Ns
|
Drug Type |
Small molecular drug
|
Therapeutic Class |
Anticancer Agents
|
Company |
AstraZeneca
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C22H24ClFN4O3
|
InChI |
InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
|
InChIKey |
XGALLCVXEZPNRQ-UHFFFAOYSA-N
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CAS Number |
CAS 184475-35-2
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PubChem Compound ID |
|
PubChem Substance ID |
532631, 7849039, 8035066, 10240807, 10318995, 11377941, 12015033, 14833109, 21317853, 24424016, 24424024, 24424026, 29215403, 29215404, 29303859, 46508649, 47646567, 49635529, 49742641, 50040863, 50100103, 53319998, 53788589, 53799235, 56312091, 56313236, 56313469, 57340492, 61127928, 81092810, 85171051, 92308715, 92717784, 93581024, 99436946, 99444469, 103024897, 103244983, 103905343, 103905344, 104418951, 104829175, 117865087, 118047033, 123105108, 124756943, 124892204, 124892205, 124892206, 125001914
|
ChEBI ID |
ChEBI:49668
|
SuperDrug ATC ID |
L01XE02
|
SuperDrug CAS ID |
cas=184475352
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Drug Resistance Mutation (DRM) |
Target and Pathway |
References |