Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03VUQ
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| Former ID |
DNC008213
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| Drug Name |
4-(4-hydroxy-benzylideneamino)-benzenesulfonamide
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| Synonyms |
4-(4-hydroxybenzylideneamino)benzenesulfonamide
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| Indication | Discovery agent | Investigative | [529203] | ||
| Structure |
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Download2D MOL |
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| Canonical SMILES |
C1=CC(=O)C=CC1=CNC2=CC=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C13H12N2O3S/c14-19(17,18)13-7-3-11(4-8-13)15-9-10-1-5-12(16)6-2-10/h1-9,15H,(H2,14,17,18)
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| InChIKey |
QNCWACMNLQTFIY-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase II | Target Info | Inhibitor | [530416] | |
| Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [529203] | ||
| KEGG Pathway | Nitrogen metabolism | ||||
| Proximal tubule bicarbonate reclamation | |||||
| Collecting duct acid secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Bile secretionhsa00590:Arachidonic acid metabolism | |||||
| Metabolic pathways | |||||
| NF-kappa B signaling pathway | |||||
| VEGF signaling pathway | |||||
| TNF signaling pathway | |||||
| Retrograde endocannabinoid signaling | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Oxytocin signaling pathway | |||||
| Regulation of lipolysis in adipocytes | |||||
| Leishmaniasis | |||||
| Pathways in cancer | |||||
| Chemical carcinogenesis | |||||
| MicroRNAs in cancer | |||||
| Small cell lung cancer | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP98:Prostaglandin Synthesis and Regulation | |||||
| Arachidonic acid metabolism | |||||
| Aryl Hydrocarbon Receptor | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Spinal Cord Injury | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| Ref 529203 | Bioorg Med Chem. 2008 Mar 1;16(5):2697-706. Epub 2007 Nov 17.Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides. | ||||
| Ref 530416 | Bioorg Med Chem Lett. 2009 Nov 1;19(21):6014-7. Epub 2009 Sep 17.Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases. | ||||
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