Drug Information

Drug General Information
Drug ID
D00JRA
Former ID
DCL000703
Drug Name
Asenapine
Synonyms
Asenapi; Asenapine [INN:BAN]; Saphris (TN); [13C,2H3]-Asenipine; Trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole; 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-met; 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3-6,7)oxepino(4,5-c)pyrrole
Drug Type
Small molecular drug
Indication Schizophrenia; Bipolar disorder [ICD9: 295, 296; ICD10:F20, F31] Approved [530677], [539399]
Company
Organon BioSciences
Structure
Download
2D MOL

3D MOL
Formula
C17H16ClNO
InChI
InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3/t14-,15-/m1/s1
InChIKey
VSWBSWWIRNCQIJ-HUUCEWRRSA-N
CAS Number
CAS 65576-45-6
PubChem Compound ID
163091
PubChem Substance ID
10255109, 14848952, 46237632, 47510131, 47805605, 79842828, 85093880, 99299533, 103603974, 104179044, 113451024, 126659506, 126685375, 135119080, 135650779, 136368088, 137272164, 140825715, 144115631, 152057475, 152343981, 160646093, 164835962, 175269541, 176484918, 223677959, 224309689, 226973261, 245261846, 251971432, 252447779
SuperDrug ATC ID
J04AD02
SuperDrug CAS ID
cas=000910861
Target and Pathway
Target(s) Hyaluronidase Target Info Modulator [556264]
References
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 539399(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 22).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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