Drug Information

Drug General Information
Drug ID
D0P3JU
Former ID
DAP000240
Drug Name
Clorazepate
Synonyms
Chlorazepate; Tranxene; Cchlorazepic acid; Chlorazepic acid; Clorazepate dipotassium; Clorazepic acid; Clorazepic acid [BAN]; Gen-xene; Novo-Clopate; Tranxene (Cherazepate dipotasium); Tranxene (TN); Novo-Clopate (TN); (Chloromethyl)(dimethyl)(tridecyloxy)silane; 7-Chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
Drug Type
Small molecular drug
Indication Anxiety disorder; Insomnia [ICD9: 300, 307.4, 327.0; ICD10:F40-F42, F51.0, G47.0] Approved [538240], [542549]
Therapeutic Class
Hypnotics and Sedatives
Company
Taro Pharmaceutical Industries Ltd
Structure
Download
2D MOL

3D MOL
Formula
C16H11ClN2O3
InChI
InChI=1S/C16H11ClN2O3/c17-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)19-14(16(21)22)15(20)18-12/h1-8,14H,(H,18,20)(H,21,22)
InChIKey
XDDJGVMJFWAHJX-UHFFFAOYSA-N
CAS Number
CAS 23887-31-2
PubChem Compound ID
2809
PubChem Substance ID
9138, 4821016, 7849641, 7978977, 8151816, 10542638, 14950450, 29221964, 46506595, 50066179, 50071296, 74906350, 96079582, 103807498, 104239421, 104301676, 117469038, 129671809, 134337554, 134994500, 137089233, 137240524, 160963973, 162311076, 163299016, 179225622, 198993218, 223365884, 224779999, 227838419, 241037568, 250143278
SuperDrug ATC ID
N05BA05
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 538240FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071852.
Ref 542549(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7548).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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