Drug Information

Drug General Information
Drug ID
D08XFV
Former ID
DAP000242
Drug Name
Flurazepam
Synonyms
Dalmadorm; Dalmane; Felison; Felmane; Flunox; Flurazepamum; Insumin; Noctosom; Paxane; Somnol; Stauroderm; Valdorm; Flurazepam HCL; Flurazepam hydrochloride; Dalmadorm (TN); Dalmane (TN); Dalmane-R; Flurazepamum [INN-Latin]; Insumin (TN); Flurazepam (JP15/INN); Flurazepam [INN:BAN:JAN]; Ro-5-6901/3; 2H-1,4-Benzodiazepin-2-one,7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, dihydrochloride; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1H-1,4-benzodiazepin-2(3H)-one; 7-Chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
Drug Type
Small molecular drug
Indication Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10:F51.0, G47.0] Approved [538223], [542199]
Therapeutic Class
Hypnotics and Sedatives
Company
West-ward Pharmaceutical Corp
Structure
Download
2D MOL

3D MOL
Formula
C21H23ClFN3O
InChI
InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
InChIKey
SAADBVWGJQAEFS-UHFFFAOYSA-N
CAS Number
CAS 17617-23-1
PubChem Compound ID
3393
PubChem Substance ID
5373981, 7847395, 7979292, 8152162, 10510931, 16847426, 26757995, 29222528, 46508451, 48416030, 49884134, 57321773, 74737372, 81065483, 103252248, 104303383, 125343184, 126666911, 127346536, 127346537, 129206359, 131302560, 134337556, 134961907, 134991466, 137005121, 139650929, 144205754, 152029390, 152146193, 160964035, 164814237, 170465018, 175265966, 177513104, 178103763, 179116700, 198993237, 221672978, 223661920, 226416782, 249949893, 252349925
SuperDrug ATC ID
N05CD01
SuperDrug CAS ID
cas=017617231
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 538223FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070344.
Ref 542199(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7188).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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