Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0LC0F
|
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| Former ID |
DNC005129
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| Drug Name |
2,3-dihydro-1H-indene-5-sulfonamide
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| Synonyms |
Indan-5-sulfonic acid amide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529417] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C9H11NO2S
|
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| Canonical SMILES |
C1CC2=C(C1)C=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C9H11NO2S/c10-13(11,12)9-5-4-7-2-1-3-8(7)6-9/h4-6H,1-3H2,(H2,10,11,12)
|
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| InChIKey |
XVQJTFMKKZBBSX-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase | Target Info | Inhibitor | [529417] | |
| Carbonic anhydrase I | Target Info | Inhibitor | [527262] | ||
| Carbonic anhydrase XIV | Target Info | Inhibitor | [529417] | ||
| Carbonic anhydrase II | Target Info | Inhibitor | [527262] | ||
| Carbonic anhydrase XII | Target Info | Inhibitor | [529417] | ||
| Pathway Interaction Database | C-MYB transcription factor network | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen | |||||
| Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon Dioxide | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| References | |||||
| Ref 527262 | Bioorg Med Chem Lett. 2004 Dec 6;14(23):5781-6.Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties. | ||||
| Ref 529417 | Eur J Med Chem. 2008 Dec;43(12):2853-60. Epub 2008 Feb 29.Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. | ||||
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