TTD | Drug: D0IO0I

Drug General Information
Drug ID	D0IO0I
Former ID	DNC008725
Drug Name	Go-Y022
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529286]
Structure		Download 2D MOL 3D MOL
Formula	C19H18O5
Canonical SMILES	COC1=C(C=CC(=C1)C=CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
InChI	1S/C19H18O5/c1-23-18-11-13(5-9-16(18)21)3-7-15(20)8-4-14-6-10-17(22)19(12-14)24-2/h3-12,21-22H,1-2H3/b7-3+,8-4+
InChIKey	ISIMGBQRFXXNON-FCXRPNKRSA-N
PubChem Compound ID	6474893
Target and Pathway
Target(s)	Cytochrome P450 2D6	Target Info	Inhibitor	[529286]
KEGG Pathway	Metabolism of xenobiotics by cytochrome P450
	Drug metabolism - cytochrome P450
	Serotonergic synapse
Reactome	Xenobiotics
WikiPathways	Metapathway biotransformation
	Tamoxifen metabolism
	Oxidation by Cytochrome P450
	Vitamin D Receptor Pathway
	Aripiprazole Metabolic Pathway
	Fatty Acid Omega Oxidation
	Codeine and Morphine Metabolism
References
Ref 529286	Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.
Ref 529286	Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.

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Drug Information