Drug Information
Drug General Information | |||||
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Drug ID |
D02DES
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Former ID |
DAP000095
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Drug Name |
Anakinra
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Synonyms |
Kineret; Kineret (TN); Anakinra (USAN/INN)
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Therapeutic Class |
Antiinflammatory Agents
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Company |
Amgen Inc
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Formula |
C759H1186N208O232S10
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CAS Number |
CAS 143090-92-0
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PubChem Substance ID | |||||
SuperDrug ATC ID |
L04AC03
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Target and Pathway | |||||
Target(s) | Interleukin 1 receptor | Target Info | Antagonist | [536369], [537496] | |
PANTHER Pathway | p38 MAPK pathway | ||||
Pathway Interaction Database | IL12-mediated signaling events | ||||
IL1-mediated signaling events | |||||
Reactome | Interleukin-1 signaling | ||||
WikiPathways | Monoamine Transport | ||||
Hypertrophy Model | |||||
MAPK Signaling Pathway | |||||
IL1 and megakaryotyces in obesity | |||||
Structural Pathway of Interleukin 1 (IL-1) | |||||
Spinal Cord Injury | |||||
Integrated Pancreatic Cancer Pathway | |||||
IL-1 signaling pathway | |||||
Interleukin-1 signaling | |||||
Apoptosis Modulation and Signaling | |||||
Serotonin Transporter Activity | |||||
References | |||||
Ref 536711 | Molecular targets of rheumatoid arthritis. Inflamm Allergy Drug Targets. 2008 Mar;7(1):53-66. | ||||
Ref 542003 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6972). |
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