Drug Information
| Drug General Information | |||||
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| Drug ID |
DXN2NH
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| Drug Name |
4-(6-(4-(4-(((2R,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-difluorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)pyridin-3-yl)-1-(1-hydroxypropan-2-yl)-1H-1,2,4-triazol-5(4H)-one
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| Synonyms |
CHEMBL1809097
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H35F2N9O5
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| Canonical SMILES |
CC(CO)N1N=CN(C1=O)c2ccc(nc2)N3CCN(CC3)c4ccc(OC[C@H]5CO[C@@](Cn6cncn6)(O5)c7ccc(F)cc7F)cc4
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| InChI |
InChI=1S/C33H35F2N9O5/c1-23(16-45)44-32(46)43(22-39-44)26-5-9-31(37-15-26)41-12-10-40(11-13-41)25-3-6-27(7-4-25)47-17-28-18-48-33(49-28,19-42-21-36-20-38-42)29-8-2-24(34)14-30(29)35/h2-9,14-15,20-23,28,45H,10-13,16-19H2,1H3/t23?,28-,33-/m0/s1
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| InChIKey |
FKBXOLXCDAOGID-PGNHVRFOSA-N
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| Target and Pathway | |||||
| Target(s) | Nitric-oxide synthase, brain | Target Info | [1587926] | ||
| Nitric oxide synthase, inducible | Target Info | [1587926] | |||
| KEGG Pathway | Arginine and proline metabolism | ||||
| Metabolic pathways | |||||
| Calcium signaling pathway | |||||
| Phagosome | |||||
| Circadian entrainment | |||||
| Long-term depression | |||||
| Salivary secretion | |||||
| Alzheimer's disease | |||||
| Amyotrophic lateral sclerosis (ALS)hsa00220:Arginine biosynthesis | |||||
| HIF-1 signaling pathway | |||||
| Peroxisome | |||||
| Salmonella infection | |||||
| Pertussis | |||||
| Leishmaniasis | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Toxoplasmosis | |||||
| Amoebiasis | |||||
| Tuberculosis | |||||
| Pathways in cancer | |||||
| Small cell lung cancer | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Arginine and Proline Metabolism | ||||
| WikiPathways | Monoamine Transport | ||||
| Myometrial Relaxation and Contraction Pathways | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Spinal Cord Injury | |||||
| Alzheimers Disease | |||||
| Effects of Nitric Oxide | |||||
| Serotonin Transporter ActivityWP619:Type II interferon signaling (IFNG) | |||||
| AGE/RAGE pathway | |||||
| References | |||||
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