Target Information
Target General Infomation | |||||
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Target ID |
T67258
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Former ID |
TTDS00378
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Target Name |
Heparin cofactor II
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Gene Name |
SERPIND1
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Synonyms |
HC-II; HLS2; Protease inhibitor leuserpin 2; SERPIND1
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Target Type |
Research
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Function |
Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
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BioChemical Class |
Serpin family
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UniProt ID | |||||
Sequence |
MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFH
KENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGK SRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSI LHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKV REYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWV NKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVP HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK NGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY EHRTSCLLFMGRVANPSRS |
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Pathways | |||||
KEGG Pathway | Complement and coagulation cascades | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
Reactome | Intrinsic Pathway of Fibrin Clot Formation | ||||
Common Pathway of Fibrin Clot Formation | |||||
WikiPathways | Complement and Coagulation Cascades | ||||
References |
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