Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| H3 --- SERT | 7-(3-(4-cyclopropylpiperazin-1-yl)propoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 4-(3,4-dichlorophenyl)-7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | (6R,10bR)-9-(3-morpholinopropoxy)-6-(pyridin-3-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)methanamine | Drug Info |
| H3 --- SERT | (2-(2-chloro-4-fluorophenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)-N-methylmethanamine | Drug Info |
| H3 --- SERT | N,N-dimethyl-3-(4-(methylthio)phenoxy)-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine | Drug Info |
| H3 --- SERT | 4-(2,5-dichlorophenyl)-7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | (6S,10bR)-6-(4-(1H-imidazol-1-yl)phenyl)-9-(3-morpholinopropoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | 7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(3-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 4-(4-(difluoromethoxy)phenyl)-7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | N,N-dimethyl-3-(4-(4-(piperidin-1-yl)but-1-ynyl)phenyl)-3-(4-(trifluoromethyl)phenoxy)propan-1-amine | Drug Info |
| H3 --- SERT | 7-(3-(4-ethylpiperazin-1-yl)propoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | N,N-dimethyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine | Drug Info |
| H3 --- SERT | 4-(4-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | 3-(3-methoxyphenoxy)-N,N-dimethyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine | Drug Info |
| H3 --- SERT | N-methyl(2-(4-(methylthio)phenoxy)-5-(4-thiomorpholinobutyl)phenyl)methanamine | Drug Info |
| H3 --- SERT | (6R,10bR)-9-(3-(piperidin-1-yl)propoxy)-6-(thiophen-3-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | N,N-dimethyl-3-phenoxy-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine | Drug Info |
| H3 --- SERT | 4-(2-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | 2-(4-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propyl)piperazin-1-yl)phenol | Drug Info |
| H3 --- SERT | (2-(3-chlorophenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)-N-methylmethanamine | Drug Info |
| H3 --- SERT | (S)-2-methyl-4-(4-(methylthio)phenyl)-7-(3-morpholinopropoxy)-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 7-(3-(4,4-difluoropiperidin-1-yl)propoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 3-(3-bromophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine | Drug Info |
| H3 --- SERT | 3-(4-fluorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine | Drug Info |
| H3 --- SERT | 4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | N-methyl(2-(4-(methylthio)phenoxy)-4-(4-morpholinobut-1-ynyl)phenyl)methanamine | Drug Info |
| H3 --- SERT | (6R,10bR)-9-(3-morpholinopropoxy)-6-(thiophen-3-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | (5-(4-(4-cyclopropylpiperazin-1-yl)but-1-ynyl)-2-(4-(methylthio)phenoxy)phenyl)-N-methylmethanamine | Drug Info |
| H3 --- SERT | 1-(4-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propyl)piperazin-1-yl)ethanone | Drug Info |
| H3 --- SERT | 4-(4-(3-((methylamino)methyl)-4-(4-(methylthio)phenoxy)phenyl)but-3-ynyl)piperazin-2-one | Drug Info |
| H3 --- SERT | 4-(4-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propyl)piperazin-1-yl)benzonitrile | Drug Info |
| H3 --- SERT | (6S,10bR)-9-(3-morpholinopropoxy)-6-(thiazol-5-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | N,N-dimethyl-3-phenyl-3-(3-(3-(piperidin-1-yl)propoxy)phenoxy)propan-1-amine | Drug Info |
| H3 --- SERT | (6R,10bR)-9-(3-(piperidin-1-yl)propoxy)-6-(pyridin-3-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | (5-(4-(4-fluoropiperidin-1-yl)but-1-ynyl)-2-(4-(methylthio)phenoxy)phenyl)-N-methylmethanamine | Drug Info |
| H3 --- SERT | (6S,10bR)-9-(3-morpholinopropoxy)-6-(thiazol-2-yl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline | Drug Info |
| H3 --- SERT | 7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | (R)-4-(4-methoxyphenyl)-2-methyl-7-(3-((S)-3-methylmorpholino)propoxy)-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 1-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propyl)piperidin-4-ol | Drug Info |
| H3 --- SERT | (4-(3-(dimethylamino)-1-phenoxypropyl)phenyl)(4-isopropylpiperazin-1-yl)methanone | Drug Info |
| H3 --- SERT | 7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | (5-(4-(4-cyclopropylpiperazin-1-yl)butyl)-2-(4-(methylthio)phenoxy)phenyl)-N-methylmethanamine | Drug Info |
| H3 --- SERT | 3-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-N,N-dimethyl-3-phenoxypropan-1-amine | Drug Info |
| H3 --- SERT | 7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methoxyphenyl)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | 4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine | Drug Info |
| H3 --- SERT | 4-(4-methoxyphenyl)-2-methyl-7-(3-(4-(thiazol-2-yl)piperazin-1-yl)propoxy)-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | 7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(4-(trifluoromethylthio)phenyl)-1,2,3,4-tetrahydroisoquinoline | Drug Info |
| H3 --- SERT | N,N-diethyl-3-(6-methyl-8-phenyl-5,6,7,8-tetrahydro-2,6-naphthyridin-3-yloxy)propan-1-amine | Drug Info |
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