Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-3-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-morpholinoethyl)phenyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indazol-3-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(pyrrolidin-1-yl)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-bromophenyl)-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(thiophen-2-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | N-isopropyl-2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide | Drug Info |
| VEGFR2 --- CDK1 | 3-{4-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-6-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-phenyl-2-(4-(pyrrolidin-1-ylmethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 3-{5-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(5-cyano-2-(4-(2-hydroxyethyl)phenylamino)pyrimidin-4-yl)benzenesulfonamide | Drug Info |
| VEGFR2 --- CDK1 | 2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholinoethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(3-morpholino-3-oxopropyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-N-[2-(dimethylamino)ethyl]pyridine-3-carboxamide | Drug Info |
| VEGFR2 --- CDK1 | 4-(3-(4-(isopropoxymethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)isoquinoline | Drug Info |
| VEGFR2 --- CDK1 | 2-(2-methyl-1H-indol-5-ylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazol-4-yl)methyl)propan-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-4-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)-5-chloropyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(2-hydroxyethyl)phenylamino)-4-(thiophen-2-yl)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazol-6-yl)morpholine | Drug Info |
| VEGFR2 --- CDK1 | 3-{5-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylamino)-[1,3,5]triazin-2-yl]-pyridin-3-ylamino}-propan-1-ol | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(2-hydroxyethyl)phenylamino)-4-(4-methoxyphenyl)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 1-(5-(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-N,N-dimethylmethanamine | Drug Info |
| VEGFR2 --- CDK1 | 2-(p-toluidino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-2-yl)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 2-(3-methoxyphenylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]butanoic acid | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phenyl)-4-(1H-indol-6-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-methoxyphenylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | N,N-diethyl-2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyrimidin-2-ylamino)phenyl)ethanol | Drug Info |
| VEGFR2 --- CDK1 | 3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-1H-imidazol-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | N-((5-(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)methyl)propan-1-amine | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(2-hydroxyethyl)phenylamino)-4-(4-(2-hydroxypropan-2-yl)phenyl)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-7-yl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 2-(4-(2-hydroxyethyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-tert-butyl-2-(4-(2-hydroxyethyl)phenylamino)pyrimidine-5-carbonitrile | Drug Info |
| VEGFR2 --- CDK1 | 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(methylamino)ethyl)phenyl)pyrimidin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | N-(3-chlorophenyl)-6-(5-{[3-(piperidin-1-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine | Drug Info |
| VEGFR2 --- CDK1 | 3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-5-(pyrimidin-5-yl)-1H-pyrazolo[3,4-b]pyridine | Drug Info |
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