Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-6-(4'-chloro-biphenyl-4-yl)-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-6-(4'-dimethylcarbamoyl-biphenyl-4-yl)-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-2-((S)-4-(4-isopropylphenyl)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pentan-2-ylamino)-1-oxobutan-2-ylamino)propanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethylamino)butan-2-yl)-N4-hydroxy-2-nonylsuccinamide | Drug Info |
| MMP2 --- MMP3 | [(S)-2-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-(4-phenylacetylamino-butyl)-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | (6S,7S)-6-[4-(4-cyano-3,5-dimethyl-phenyl)-3,6-dihydro-2H-pyridine-1-carbonyl]-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP3 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-4-(3-methoxy-phenyl)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-butyl]-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | (4-Benzoylamino-butyl)-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | 4'-[(3R,5S)-5-Carboxy-3-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-nonyl]-biphenyl-4-carboxylic acid methyl ester | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)-6-phenylhexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4'-formyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | 2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide | Drug Info |
| MMP2 --- MMP3 | (R)-N1-((S)-1-(cyclopentylamino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide | Drug Info |
| MMP2 --- MMP3 | (R)-1-(1-(methylamino)-1-oxo-3-phenylpropan-2-yl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea | Drug Info |
| MMP2 --- MMP3 | N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-acetamide | Drug Info |
| MMP2 --- MMP3 | N-[2-(4'-Cyano-biphenyl-4-yloxy)-ethyl]-N-hydroxy-acetamide | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-[(S)-2,2-dimethyl-1-(pyridin-4-ylcarbamoyl)-propylcarbamoyl]-6-(4'-fluoro-biphenyl-4-yl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | 2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide | Drug Info |
| MMP2 --- MMP3 | (R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-phenyl-propylamino]-octanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4'-methanesulfonyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-6-Biphenyl-3-yl-2-butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | 3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomethyl-pentanoylamino)-propionylamino]-propionic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[4'-(1H-imidazol-2-yl)-biphenyl-4-yl]-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)-6-phenylhexanoic acid | Drug Info |
| MMP2 --- MMP3 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((R)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | (R)-2-[3-(2-chloro-biphenyl-4-yl)-propyl]-N*1*-[(S)-2,2-dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-succinamide | Drug Info |
| MMP2 --- MMP3 | (R)-N4-hydroxy-N1-((S)-1-((R)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-yl)-2-(3-phenylpropyl)succinamide | Drug Info |
| MMP2 --- MMP3 | 2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfonyl)-N-hydroxy-acetamide | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-6-(2',6'-dimethyl-biphenyl-4-yl)-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-N1-((S)-1-(tert-butylamino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(2-carboxyethylamino)-3-cyclohexyl-1-oxopropan-2-yl)carbamoyl)-6-p-tolylhexanoic acid | Drug Info |
| MMP2 --- MMP3 | 2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine-1-sulfonyl]-N-hydroxy-2-methyl-propionamide | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(3'-trifluoromethyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[4-(tetrahydro-furan-2-yl)-phenyl]-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-(4'-methylsulfanyl-biphenyl-4-yl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-6-(4-chloro-phenyl)-3-{(S)-2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (4'-cyano-biphenyl-4-ylmethyl)-amide | Drug Info |
| MMP2 --- MMP3 | [4-(3-Ethyl-ureido)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-6-[4'-(1H-tetrazol-5-yl)-biphenyl-4-yl]-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide | Drug Info |
| MMP2 --- MMP3 | (R)-N*1*-[(S)-2,2-dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-2-[2-(4'-fluoro-biphenyl-4-yl)-ethyl]-N*4*-hydroxy-succinamide | Drug Info |
| MMP2 --- MMP3 | (3S,4S)-N-hydroxy-4-(4-((2-methyl-1H-indol-3-yl)methyl)benzamido)-1-(prop-2-ynyl)pyrrolidine-3-carboxamide | Drug Info |
| MMP2 --- MMP3 | (R)-N*1*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-[3-(2-trifluoromethyl-biphenyl-4-yl)-propyl]-succinamide | Drug Info |
| MMP2 --- MMP3 | [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid | Drug Info |
| MMP2 --- MMP3 | (2S,4R)-2-Butyl-6-(3',5'-dichloro-biphenyl-4-yl)-4-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-hexanoic acid | Drug Info |
| MMP2 --- MMP3 | (2R,3S)-N*4*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethyl-propyl]-2,N*1*-dihydroxy-3-(3-phenyl-propyl)-succinamide | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(tert-butylamino)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)-6-phenylhexanoic acid | Drug Info |
| MMP2 --- MMP3 | (R)-3-(((S)-1-(4-amino-4-oxobutylamino)-3-cyclohexyl-1-oxopropan-2-yl)carbamoyl)-6-phenylhexanoic acid | Drug Info |
| MMP2 --- MMP3 | N-((5-benzyl-2,4,6-trioxo-hexahydropyrimidin-5-yl)methyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide | Drug Info |
| MMP2 --- MMP3 | (2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-N*1*-hydroxy-3-isobutyl-succinamide | Drug Info |
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