Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| HDAC1 --- HD6 | 6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthalen-1-ylmethyl)-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)hexanoic acid | Drug Info |
| HDAC1 --- HD6 | (E)-(1S,7R,10S,21R)-7-isopropyl-21-methyl-2-oxa-12,13-dithia-5,8,20,23-tetraaza-bicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentaone | Drug Info |
| HDAC1 --- HD6 | 2-(4-Methoxyphenyl)-2-oxoethyl Dithiobutyrate | Drug Info |
| HDAC1 --- HD6 | 2-[4-(4-Chloro-phenylsulfamoyl)-phenyl]-2-oxoethyl ethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylcarbamoyl)-methyl]-thiophen-2-yl}-ethyl Trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | N-Hydroxy-5-[5-oxo-5-(phenylamino)pentyl]isoxazole-3-carboxamide | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(5-methyl-1-phenethyl-4-phenyl-1H-imidazol-2-yl)phenyl)acrylamide | Drug Info |
| HDAC1 --- HD6 | (S)-benzyl 1-(2-phenylthiazol-4-yl)-5-(sulfamoylamino)pentylcarbamate | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-(4-Methanesulfonylamino-phenyl)-2-oxoethyl Trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-[4-(4-methoxy-phenylsulfamoyl)-phenyl]-2-oxoethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | N-(1-(pyridin-4-yl)ethyl)-5-(2,2,2-trifluoroacetyl)thiophene-2-carboxamide | Drug Info |
| HDAC1 --- HD6 | (S)-2-(4-(dimethylamino)benzamido)-N8-hydroxy-N1-(quinolin-8-yl)octanediamide | Drug Info |
| HDAC1 --- HD6 | 2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | 3-(3-(1-(2-(diisopropylamino)ethyl)-1H-benzo[d]imidazol-2-yl)phenyl)-N-hydroxyacrylamide | Drug Info |
| HDAC1 --- HD6 | (E)-(1S,7R,10S,21R)-7,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentaone | Drug Info |
| HDAC1 --- HD6 | 4-[5-(Trifluoroacetyl)thiophen-2-yl]benzonitrile | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-oxo-2-[4-(2-phenoxy-ethylcarbamoyl)-phenyl]-ethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-(piperidin-4-ylmethyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| HDAC1 --- HD6 | methyl 4-((4-(3-(hydroxyamino)-3-oxoprop-1-enyl)benzylideneaminooxy)methyl)benzoate | Drug Info |
| HDAC1 --- HD6 | tert-butyl 4-(3-(2-(4-(3-(hydroxycarbamoyl)isoxazol-5-yl)phenylamino)-2-oxoethylcarbamoyl)isoxazol-5-yl)phenylcarbamate | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(4-(5-(morpholinomethyl)isoxazol-3-yl)phenyl)acrylamide hydrochloride | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-oxo-2-{4-[(1-pyridine-3-yl-methanoyl)-amino]-phenyl}-ethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | (S)-2-(phenylmethylsulfonamido)-N-(4-phenylthiazol-2-yl)-6-(sulfamoylamino)hexanamide | Drug Info |
| HDAC1 --- HD6 | N-Ethyl S-2-(4-methoxy-phenyl)-2-oxoethyl thiocarbamate | Drug Info |
| HDAC1 --- HD6 | 3-(3-(4,5-dimethyl-1-phenethyl-1H-imidazol-2-yl)phenyl)-N-hydroxyacrylamide | Drug Info |
| HDAC1 --- HD6 | N-Hydroxy-8-(3-hydroxy-4-(2-hydroxycarbamoylethyl)-2-isopentyl-phenoxy)octanamide | Drug Info |
| HDAC1 --- HD6 | (S)-pyridin-3-ylmethyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(sulfamoylamino)hexan-2-ylcarbamate | Drug Info |
| HDAC1 --- HD6 | 6-((5S,8S,11S)-11-((1H-indol-3-yl)methyl)-2,2-dimethyl-8-(naphthalen-1-ylmethyl)-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)hexanoic acid | Drug Info |
| HDAC1 --- HD6 | 3-(4-(((2-(1H-indol-2-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide | Drug Info |
| HDAC1 --- HD6 | (R)-3-(3-(1-(1-ethylpiperidin-3-yl)-4,5-dimethyl-1H-imidazol-2-yl)phenyl)-N-hydroxyacrylamide | Drug Info |
| HDAC1 --- HD6 | 2-Phenoxyethyl 2-(4-methoxyphenyl)-2-oxoethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | (2E, 4E)-9-Benzo[1,3]dioxol-5-yl-nona-2,4-dienoic acid hydroxylamine | Drug Info |
| HDAC1 --- HD6 | 1-(5-(4-(5-chloro-2-methoxyphenyl)piperazine-1-carbonyl)thiophen-2-yl)-2,2,2-trifluoroethanone | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-[4-(N-4-methoxy-phenyl-N-methyl-sulfamoyl)-phenyl]-2-oxoethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | 6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-isobutyl-2-methyl-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)-N-hydroxyhexanamide | Drug Info |
| HDAC1 --- HD6 | Azithromycin-N-benzyltriazolyloctahydroxamic Acid | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(3-(1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| HDAC1 --- HD6 | 6-(9H-carbazol-9-yl)-N-hydroxyhexanamide | Drug Info |
| HDAC1 --- HD6 | (S)-2-(8-hydroxycarbamoyl-octanoylamino)-3-[1,1':4',1'']terphenyl-4-yl-propionic acid methyl ester | Drug Info |
| HDAC1 --- HD6 | (6R,9R,12R,16S)-6-isopropyl-16-((E)-4-mercapto-but-1-enyl)-9,12-dimethyl-1-oxa-4,7,10,13-tetraaza-cyclohexadecane-2,5,8,11,14-pentaone | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-[3-(4-methoxy-phenylsulfamoyl)-phenyl]-2-oxoethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | (R)-N-hydroxy-3-(3-(1-(piperidin-3-yl)-1H-benzo[d]imidazol-2-yl)phenyl)acrylamide | Drug Info |
| HDAC1 --- HD6 | Ethyl 2-oxo-2-{3-[(pyridine-3-carbonyl)-amino]-phenyl}-ethyl trithiocarbonate | Drug Info |
| HDAC1 --- HD6 | ethyl 2-(5-(2-(4-methoxyphenylamino)-2-oxoethyl)thiophen-2-yl)-2-oxoethyl trithiocarbonoate | Drug Info |
| HDAC1 --- HD6 | (S)-benzyl 1-(2-(4-(2-(dimethylamino)ethoxy)phenyl)thiazol-4-yl)-5-(sulfamoylamino)pentylcarbamate | Drug Info |
| HDAC1 --- HD6 | N-hydroxy-3-(4-((perfluorobenzyloxyimino)methyl)phenyl)acrylamide | Drug Info |
| HDAC1 --- HD6 | 6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-isobutyl-2-methyl-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)hexanoic acid | Drug Info |
| HDAC1 --- HD6 | 6-((2S,5S,8S,11S)-2-(5-acetamidopentyl)-11-isobutyl-8-(naphthalen-1-ylmethyl)-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)hexanoic acid | Drug Info |
| HDAC1 --- HD6 | (2E,4E,8E)-9-Benzo[1,3]dioxol-5-yl-nona-2,4,8-trienoic acid hydroxylamine | Drug Info |
| HDAC1 --- HD6 | (S)-benzyl 1-(1-methyl-5-phenyl-1H-1,2,4-triazol-3-yl)-5-(sulfamoylamino)pentylcarbamate | Drug Info |
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