Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-pyridin-3-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-{[(3-Hydroxy-4-propoxybenzyl)amino]methylene}-6-iodoisoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | N-(2-(diethylamino)ethyl)-3-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide | Drug Info |
| CDK2 --- CDK4 | 3-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Drug Info |
| CDK2 --- CDK4 | 1-Dimethylamino-3-{4-[4-(2-fluoro-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | GW781673X | Drug Info |
| CDK2 --- CDK4 | (3-Methoxy-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | N-(5-(2-(cyclohexyloxy)-5-methylpyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine | Drug Info |
| CDK2 --- CDK4 | 3-[4-(4-Methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Drug Info |
| CDK2 --- CDK4 | N-[(4Z)-1,3-Dioxo-4-({[4-piperidin-1-ylmethyl]phenyl}amino)-methylene]-1,2,3,4-tetrahydroisoquinolin-6-yl]acetamide | Drug Info |
| CDK2 --- CDK4 | 4-(4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL485240 | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL99689 | Drug Info |
| CDK2 --- CDK4 | CHEMBL485618 | Drug Info |
| CDK2 --- CDK4 | N-(4-nitrophenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-2,4-dimethyl-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-[4-(6-methoxy-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | (4-butoxy-1H-indazol-5-yl)(2,6-difluoro-4-methylphenyl)methanone | Drug Info |
| CDK2 --- CDK4 | (3,5-Dimethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL317378 | Drug Info |
| CDK2 --- CDK4 | [4-(6-Methyl-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-(3-trifluoromethyl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL433068 | Drug Info |
| CDK2 --- CDK4 | 3-((2,5-Dichloro-phenyl)-{2-[4-(3-dimethylamino-2-hydroxy-propoxy)-phenylamino]-pyrimidin-4-yl}-amino)-propionitrile | Drug Info |
| CDK2 --- CDK4 | 1-{4-[4-(2-Chloro-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-yl]methyl}-amino)methylene]-6-iodoisoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide | Drug Info |
| CDK2 --- CDK4 | 4-[4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-ylamino]-benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Fluoro-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid amide | Drug Info |
| CDK2 --- CDK4 | N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | N-[4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-yl]-acetamide | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzonitrile | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | Drug Info |
| CDK2 --- CDK4 | (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-[4-(6-methyl-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 1-{4-[4-(2-Bromo-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | 1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)phenoxy)propan-2-ol | Drug Info |
| CDK2 --- CDK4 | CHEMBL101119 | Drug Info |
| CDK2 --- CDK4 | N-cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | GW806290X | Drug Info |
| CDK2 --- CDK4 | 4-(4-(4-methyl-2-(methylamino)thiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | CHEMBL99948 | Drug Info |
| CDK2 --- CDK4 | CHEMBL322019 | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-5-nitro-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL103355 | Drug Info |
| CDK2 --- CDK4 | 4-(6-isopropoxypyrazolo[1,5-b]pyridazin-3-yl)-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | (8-Isopropyl-7-methoxy-quinazolin-2-yl)-(4-piperidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL101311 | Drug Info |
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