Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- AuroraA | 8-[(3-Acetylphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-[(4-morpholin-4-ylphenyl)amino]-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-(5-isobutyryl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzo[d][1,3]dioxole-5-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-[(4-Acetylphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 4-methyl-N-(5-(quinoline-8-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide | Drug Info |
| CDK2 --- AuroraA | N-(2,6-Diethylphenyl)-8-({2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)carbonyl]phenyl}amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Chlorophenylamino)-5-methylpyrimidin-4-yl}-N-{1-phenyl-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Phenyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]-quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-[(2-Fluorophenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-{[3-(morpholin-4-ylmethyl)phenyl]-amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-{[2-(methylamino)phenyl]amino}-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(Benzo[d]1,3-dioxolylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({3-[(4-methylpiperazin-1-yl)methyl]-phenyl}amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({3-[(1-methylpiperidin-4-yl)oxy]phenyl}-amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Hydroxyphenylamino)-5-methylpyrimidin-4-yl}-N-{1-phenyl-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-{[4-(morpholin-4-ylmethyl)phenyl]-amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(4-Chloro-2-fluorophenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-[(3-morpholin-4-ylphenyl)amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({4-[(1-methylpiperidin-4-yl)oxy]phenyl}-amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Chlorophenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-(Phenylamino)-1-(propan-2-yl)-4,5-dihydro-1H-pyrazolo[4,3-h]-quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Methylphenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Ethylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-[(4-Methoxyphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-[(2-Methoxyphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Chlorophenyl)-2-hydroxyethyl}-4-{5-methyl-2(5,6,7,8-tetrhydronaphthalen-1-ylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-[(4-Carbamoyl-2-methoxyphenyl)amino]-N-(2,6-diethylphenyl)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-(5-acetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-methoxybenzamide | Drug Info |
| CDK2 --- AuroraA | 8-[(2-Aminophenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-[(4-morpholin-4-ylphenyl)amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-Benzyl-1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-(5-acetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-fluorobenzamide | Drug Info |
| CDK2 --- AuroraA | N-cyclopropyl-1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-{[3-(Dimethylamino)phenyl]amino}-N,1,4,4-tetramethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(3-Fluoro-2-methylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-(3-chlorophenyl)-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-(5-acetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide | Drug Info |
| CDK2 --- AuroraA | 8-({3-[(Dimethylamino)methyl]phenyl}amino)-N,1,4,4-tetramethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N,1,4,4-Tetramethyl-8-({4-[(4-methylpiperazin-1-yl)methyl]-phenyl}amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid | Drug Info |
| CDK2 --- AuroraA | 8-[(3-Methoxyphenyl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (R)-N-(2-Hydroxyl-1-phenylethyl)-4-{5-methyl-2-(phenylamino)-pyrimidin-4-yl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-N-{1-(3-Chlorophenyl)-2-hydroxyethyl}-4-{-2-(2,3-dihydrobenzo[b][1,4]dioxin-5-ylamino)-5-methylpyrimidin-4-yl}-1Hpyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 8-(Phenylamino)-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | (S)-4-{2-(2-Methylphenylamino)-5-methylpyrimidin-4-yl}-N-{1-phenyl-2-hydroxyethyl}-1H-pyrrole-2-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-{[4-(trifluoromethyl)phenyl]amino}-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | N-(5-acetyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-methylbenzamide | Drug Info |
| CDK2 --- AuroraA | 1,4,4-Trimethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
| CDK2 --- AuroraA | 1-Methyl-8-[(2-methylphenyl)amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | Drug Info |
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