Drug General Information
Drug ID
DXVX2J
Drug Name
1-(3',5'-dimethylphenyl)-3-(4-methyl-2-oxo-2H-chromen-7-yl)urea
Synonyms
CHEMBL1957187
Indication Discovery agent Investigative [1587926]
Formula
C19H18N2O3
Canonical SMILES
CC1=CC(=O)Oc2cc(NC(=O)Nc3cc(C)cc(C)c3)ccc12
InChI
InChI=1S/C19H18N2O3/c1-11-6-12(2)8-15(7-11)21-19(23)20-14-4-5-16-13(3)9-18(22)24-17(16)10-14/h4-10H,1-3H3,(H2,20,21,23)
InChIKey
IPGFTURWEBMLSG-UHFFFAOYSA-N
Target and Pathway
Target(s) Carbonic anhydrase IX Target Info [1587926]
Carbonic anhydrase XII Target Info [1587926]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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