Drug General Information
Drug ID
D0Z2WQ
Former ID
DNC001183
Drug Name
Quinelorane
Drug Type
Small molecular drug
Indication Male sexual disorders [ICD10:F52] Discontinued in Phase 3 [543323], [544908]
Structure
Download
2D MOL

3D MOL

Formula
C14H22N4
InChI
InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1
InChIKey
TUFADSGTJUOBEH-ZWNOBZJWSA-N
CAS Number
CAS 97466-90-5
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) D(3) dopamine receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapse
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, Other
References
Ref 543323(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 954).
Ref 544908Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001472)

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