Drug Information
Drug General Information | |||||
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Drug ID |
D0Y4ZI
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Former ID |
DIB001809
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Drug Name |
Silicon-modified indomethacin
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Synonyms |
Silexsyn; RND-100; SiM-100; Silicon-modified indomethacin (cancer); Silicon-modified indometacin (cancer), Silamed; Silicon-modified indomethacin (cancer), Silamed
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Indication | Arthritis [ICD9: 710-719; ICD10:M00-M25] | Investigative | [543413] | ||
Company |
Silamed Inc
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Structure |
Download2D MOL |
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Canonical SMILES |
C(=O)(Cc1c(n(c2c1cc(cc2)OC)C(=O)c1ccc(cc1)Cl)C)NCCC[Si]<br />(C)(C)C
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [543413] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References |
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