Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y4PL
|
||||
| Former ID |
DIB014572
|
||||
| Drug Name |
QAP-642
|
||||
| Synonyms |
CCR3 antagonist (allergic rhinitis), Novartis
|
||||
| Indication | Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] | Terminated | [1] | ||
| Company |
Novartis AG
|
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| Target and Pathway | |||||
| Target(s) | C-C chemokine receptor type 3 | Target Info | Antagonist | [2] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| Chemokine signaling pathway | |||||
| Viral carcinogenesis | |||||
| NetPath Pathway | IL3 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Reactome | Chemokine receptors bind chemokines | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| IL1 and megakaryotyces in obesity | |||||
| IL-3 Signaling Pathway | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023202) | ||||
| REF 2 | New Drugs and Targets for Asthma and COPD. T.T. Hansel, P.J. Barnes. 2010. Page 158. | ||||
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