Drug Information

Drug General Information
Drug ID
D0W5WG
Former ID
DNC008660
Drug Name
JNJ-1661010
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468260]
Structure
Download
2D MOL

3D MOL
Formula
C19H19N5OS
InChI
InChI=1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25)
InChIKey
BHBOSTKQCZEAJM-UHFFFAOYSA-N
PubChem Compound ID
2809273
PubChem Substance ID
3267393, 5376539, 8334260, 12057226, 24259607, 26729443, 40177582, 48061254, 51525486, 88849348, 92262667, 103012314, 103586821, 104100667, 111423125, 117572635, 125145653, 125515447, 134345865, 135698019, 137604757, 139510995, 152159641, 162160284, 162248699, 162312792, 162569742, 164194100, 172113648, 178101892, 179332136, 198939445, 204370507, 223400411, 223490032, 224229613, 227401620, 241376345, 246708308, 252125965, 252157139, 252262425, 252438618, 252472163
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [529638]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signaling
PANTHER Pathway Anandamide degradation
References
Ref 468260(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5206).
Ref 529638Bioorg Med Chem Lett. 2008 Sep 1;18(17):4838-43. Epub 2008 Jul 25.Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase.

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