Drug Information

Drug General Information
Drug ID
D0U3LS
Former ID
DAP000244
Drug Name
Triazolam
Synonyms
Clorazolam; Halcion; Hypnostat; Novidorm; Novodorm; Songar; Triazolamum; Trilam; Apo Triazo; Apotex Brand of Triazolam; Gen Triazolam; Genpharm Brand of Triazolam; Gerard Brand of Triazolam; Pfizer Brand of Triazolam; Triazolam Pfizer Brand; TGAR01H; U 33030; Alti-Triazolam; Apo-Triazo; Gen-Triazolam; Halcion (TN); Halcion (triazolam); Hypam (TN); Novo-Triolam; Triazolamum [INN-Latin]; Trilam (TN); U 33,030; U-33030; U33,030; Apo-Triazo (TN); U-33,030; Triazolam (JAN/USP/INN); Triazolam [USAN:BAN:INN:JAN]; 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-[2-chlorophenyl]-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Drug Type
Small molecular drug
Indication Insomnia [ICD9: 307.41, 307.42, 327.0, 780.51, 780.52; ICD10:F51.0, G47.0] Approved [536565], [542336]
Therapeutic Class
Hypnotics and Sedatives
Company
Upjohn Corporation
Structure
Download
2D MOL

3D MOL
Formula
C17H12Cl2N4
InChI
InChI=1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
InChIKey
JOFWLTCLBGQGBO-UHFFFAOYSA-N
CAS Number
CAS 28911-01-5
PubChem Compound ID
5556
PubChem Substance ID
5663633, 7847453, 7849624, 7980828, 8153415, 10517205, 12013397, 14875826, 24900602, 29214869, 29224597, 46509147, 50057244, 50113071, 53789234, 57322838, 58107043, 75839501, 85209509, 103189071, 103856603, 103916143, 104309572, 125536835, 128303523, 134337558, 134996744, 136949649, 137005119, 143051050, 144206170, 160964236, 164765748, 164765749, 175268086, 176262073, 178103886, 179116931, 184580915, 198991636, 210279816, 210282139, 223366877, 223454573, 224247842, 226416360, 250118403, 252357765
ChEBI ID
ChEBI:9674
SuperDrug ATC ID
N05CD05
SuperDrug CAS ID
cas=028911015
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 536565What every dentist should know about the "z-sedatives". J Mass Dent Soc. 2007 Fall;56(3):44-5.
Ref 542336(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7313).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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