Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T5MO
|
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| Former ID |
DNC002540
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| Drug Name |
5alpha-Androstan-3,17-Dione
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H28O2
|
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| Canonical SMILES |
CC12CCC(=O)CC1CCC3C2CCC4(C3CCC4=O)C
|
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| InChI |
1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12-,14-,15-,16-,18-,19-/m0/s1
|
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| InChIKey |
RAJWOBJTTGJROA-WZNAKSSCSA-N
|
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| CAS Number |
CAS 846-46-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
2382, 3943, 75251, 108764, 831357, 841384, 854748, 7885430, 8145054, 9377310, 12161429, 15492483, 25621459, 30426054, 46505490, 46508701, 50897570, 57400000, 85300779, 92298501, 103935286, 104246631, 113476485, 126523661, 126722984, 129100947, 135034420, 137016148, 139692791, 152095020, 160964805, 162921172, 164835841, 172847800, 179322734, 198976101, 224517174, 227137944, 241148567, 250112785
|
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| Target and Pathway | |||||
| Target(s) | 3-beta-HSD | Target Info | Inhibitor | [1] | |
| Estradiol 17 beta-dehydrogenase 1 | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Superpathway of steroid hormone biosynthesis | ||||
| Estradiol biosynthesis I | |||||
| KEGG Pathway | Steroid hormone biosynthesis | ||||
| Metabolic pathways | |||||
| Ovarian steroidogenesis | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Reactome | The canonical retinoid cycle in rods (twilight vision) | ||||
| WikiPathways | Steroid Biosynthesis | ||||
| Metabolism of steroid hormones and vitamin D | |||||
| Prostate Cancer | |||||
| References | |||||
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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