| Drug General Information |
| Drug ID |
D0P6PQ
|
| Former ID |
DNC008121
|
| Drug Name |
THIOCTIC ACID
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C8H14O2S2
|
| Canonical SMILES |
C1CSSC1CCCCC(=O)O
|
| InChI |
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
|
| InChIKey |
AGBQKNBQESQNJD-UHFFFAOYSA-N
|
| CAS Number |
CAS 62-46-4
|
| PubChem Compound ID |
|
| SuperDrug ATC ID |
A16AX01
|
| Target and Pathway |
| Target(s) |
Prostaglandin G/H synthase 2 |
Target Info |
Inhibitor |
[1]
|
|---|
| Acetylcholinesterase |
Target Info |
Inhibitor |
[2]
|
|
BioCyc Pathway
|
Aspirin-triggered lipoxin biosynthesis
|
|
Aspirin triggered resolvin D biosynthesis
|
|
C20 prostanoid biosynthesis
|
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Aspirin triggered resolvin E biosynthesis
|
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KEGG Pathway
|
Arachidonic acid metabolism
|
|
Metabolic pathways
|
|
NF-kappa B signaling pathway
|
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VEGF signaling pathway
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TNF signaling pathway
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Retrograde endocannabinoid signaling
|
|
Serotonergic synapse
|
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Ovarian steroidogenesis
|
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Oxytocin signaling pathway
|
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Regulation of lipolysis in adipocytes
|
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Leishmaniasis
|
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Pathways in cancer
|
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Chemical carcinogenesis
|
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MicroRNAs in cancer
|
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Small cell lung cancerhsa00564:Glycerophospholipid metabolism
|
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Cholinergic synapse
|
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NetPath Pathway
|
IL1 Signaling Pathway
|
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TSH Signaling Pathway
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IL4 Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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IL5 Signaling Pathway
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PANTHER Pathway
|
Endothelin signaling pathway
|
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Inflammation mediated by chemokine and cytokine signaling pathway
|
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Toll receptor signaling pathway
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CCKR signaling map STP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
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Muscarinic acetylcholine receptor 2 and 4 signaling pathway
|
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Nicotinic acetylcholine receptor signaling pathway
|
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Pathway Interaction Database
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
|
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S1P1 pathway
|
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C-MYB transcription factor network
|
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Signaling mediated by p38-alpha and p38-beta
|
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Calcium signaling in the CD4+ TCR pathwayatf2_pathway:ATF-2 transcription factor network
|
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PathWhiz Pathway
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Arachidonic Acid MetabolismPW000048:Phospholipid Biosynthesis
|
|
WikiPathways
|
Prostaglandin Synthesis and Regulation
|
|
Arachidonic acid metabolism
|
|
Aryl Hydrocarbon Receptor
|
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Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
|
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Spinal Cord Injury
|
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Integrated Pancreatic Cancer Pathway
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Eicosanoid Synthesis
|
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Selenium Micronutrient NetworkWP727:Monoamine Transport
|
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Biogenic Amine Synthesis
|
|
Acetylcholine Synthesis
|
| References |
| REF 1 | Eur J Med Chem. 2008 Jun;43(6):1152-9. Epub 2007 Sep 22.Investigations concerning the COX/5-LOX inhibiting and hydroxyl radical scavenging potencies of novel 4,5-diaryl isoselenazoles. |
|---|
| REF 2 | J Med Chem. 2008 Feb 14;51(3):347-72. Epub 2008 Jan 9.Multi-target-directed ligands to combat neurodegenerative diseases. |
|---|
