Drug General Information
Drug ID	D0O0DF
Former ID	DIB004410
Drug Name	Lirequinil
Synonyms	Ro-41-3696
Drug Type	Small molecular drug
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Discontinued in Phase 2	[545048]
Company	Roche Holding AG
Structure		Download 2D MOL 3D MOL
Formula	C26H25ClN2O3
Canonical SMILES	c1(c2n(c(=O)c(c1)c1ccccc1)CCc1c2cc(cc1)Cl)C(=O)N1C[C@H]<br />(CC1)OCC
CAS Number	CAS 143943-73-1
PubChem Compound ID	3045375
Target and Pathway
Target(s)	Peripheral-type benzodiazepine receptor	Target Info	Agonist	[534064]
KEGG Pathway	Neuroactive ligand-receptor interaction
	HTLV-I infection
References
Ref 545048	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001968)
Ref 534064	Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35(8):821-9.

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