Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M9IQ
|
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| Former ID |
DNC010205
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| Drug Name |
Sodium N-methylphenylaminomethanesulfonate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C8H10NNaO3S
|
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| Canonical SMILES |
CN(CS(=O)(=O)[O-])C1=CC=CC=C1.[Na+]
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| InChI |
1S/C8H11NO3S.Na/c1-9(7-13(10,11)12)8-5-3-2-4-6-8;/h2-6H,7H2,1H3,(H,10,11,12);/q;+1/p-1
|
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| InChIKey |
XIDHWXUDYZMZID-UHFFFAOYSA-M
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase IX | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase XII | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Nitrogen metabolismhsa00910:Nitrogen metabolism | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | ||||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | ||||
| Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide | |||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Reversible Hydration of Carbon Dioxide | |||||
| Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2009 Oct 15;17(20):7093-9. Epub 2009 Sep 6.Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XIIover the cytosolic isoforms I and II. | ||||
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