Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J6RQ
|
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| Former ID |
DNC008724
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| Drug Name |
1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H14O3
|
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| Canonical SMILES |
C1=CC(=CC=C1C=CC(=O)C=CC2=CC=C(C=C2)O)O
|
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| InChI |
1S/C17H14O3/c18-15-7-1-13(2-8-15)5-11-17(20)12-6-14-3-9-16(19)10-4-14/h1-12,18-19H/b11-5+,12-6+
|
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| InChIKey |
FTEGUKWEUQPKIS-YDWXAUTNSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 2D6 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Metabolism of xenobiotics by cytochrome P450 | ||||
| Drug metabolism - cytochrome P450 | |||||
| Serotonergic synapse | |||||
| Reactome | Xenobiotics | ||||
| WikiPathways | Metapathway biotransformation | ||||
| Tamoxifen metabolism | |||||
| Oxidation by Cytochrome P450 | |||||
| Vitamin D Receptor Pathway | |||||
| Aripiprazole Metabolic Pathway | |||||
| Fatty Acid Omega Oxidation | |||||
| Codeine and Morphine Metabolism | |||||
| References | |||||
| REF 1 | Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues. | ||||
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