| Drug General Information |
| Drug ID |
D0J4CB
|
| Former ID |
DNC011025
|
| Drug Name |
1-(METHOXYMETHYL)-6-(NAPHTHALEN-2-YL)-3-AZABICYCLO[4.1.0]HEPTANE (ENANTIOMERIC MIX)
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C18H21NO
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Cytochrome P450 3A4 |
Target Info |
Inhibitor |
[1]
|
|---|
| Cytochrome P450 2D6 |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Steroid hormone biosynthesis
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Linoleic acid metabolism
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Retinol metabolism
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Metabolism of xenobiotics by cytochrome P450
|
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Drug metabolism - cytochrome P450
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Drug metabolism - other enzymes
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Metabolic pathways
|
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Bile secretion
|
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Chemical carcinogenesishsa00980:Metabolism of xenobiotics by cytochrome P450
|
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Serotonergic synapse
|
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PathWhiz Pathway
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Caffeine Metabolism
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Retinol Metabolism
|
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Reactome
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Xenobiotics
|
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Aflatoxin activation and detoxificationR-HSA-211981:Xenobiotics
|
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WikiPathways
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Metapathway biotransformation
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Aflatoxin B1 metabolism
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Estrogen metabolism
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Benzo(a)pyrene metabolism
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Tamoxifen metabolism
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Tryptophan metabolism
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Oxidation by Cytochrome P450
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Nuclear Receptors in Lipid Metabolism and Toxicity
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Nuclear Receptors Meta-Pathway
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Farnesoid X Receptor Pathway
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Vitamin D Receptor Pathway
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Felbamate Metabolism
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Lidocaine metabolism
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Nifedipine Activity
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Colchicine Metabolic Pathway
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Irinotecan Pathway
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Drug Induction of Bile Acid Pathway
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Fatty Acid Omega Oxidation
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Codeine and Morphine MetabolismWP702:Metapathway biotransformation
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Aripiprazole Metabolic Pathway
|
|
Codeine and Morphine Metabolism
|
| References |
| REF 1 | J Med Chem. 2010 Jul 8;53(13):4989-5001.6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor. |
|---|
