Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0IT2X
|
||||
Former ID |
DAP000975
|
||||
Drug Name |
Carprofen
|
||||
Synonyms |
Carprofene; Carprofeno; Carprofenum; Imadyl; Ridamyl; Rimadyl; Carprofeno [Spanish]; C 5720; Ro 205720; C-5720; Carprofene [INN-French]; Carprofeno [INN-Spanish]; Carprofenum [INN-Latin]; Rimadyl (TN); Ro 20-5720; Carprofen (USAN/INN); Carprofen [USAN:INN:BAN]; Ro 20-5720/000; Ro-20-5720; Ro-20-5720/000; (+-)-6-Chloro-alpha-methylcarbazole-2-acetic acid; (+-)-isomer of carprofen; (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid; (+/-)-6-Chloro-.alpha.-methylcarbazole-2-acetic acid; (-)-6-Chlor-alpha-methyl-2-carbazolessigsaeure; 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid; 2-(6-Chloro-9H-carbazol-2-yl)propanoic acid; 6-Chlor-alpha-methyl-carbazol-2-essigsaeure; 6-Chlor-alpha-methyl-carbazol-2-essigsaeure [German]; 6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid; 6-Chloro-alpha-methylcarbazole-2-acetic acid; 9H-Carbazole-2-acetic acid, 6-chloro-.al
|
||||
Drug Type |
Small molecular drug
|
||||
Therapeutic Class |
Analgesics
|
||||
Company |
Pfizer Pharmaceuticals
|
||||
Structure |
Download2D MOL |
||||
Formula |
C15H12ClNO2
|
||||
InChI |
InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)
|
||||
InChIKey |
PUXBGTOOZJQSKH-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 53716-49-7
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
147404, 224736, 7387300, 8151706, 11372077, 11374733, 11484848, 11489052, 11490754, 11492852, 12013355, 14824217, 17397550, 24860673, 25623932, 26612250, 26679932, 26748565, 26748566, 29221741, 46505357, 48110633, 49901603, 49901604, 50085988, 51138619, 57321383, 57648952, 85174420, 85556037, 92124308, 92307546, 92719046, 99215020, 103159169, 103409544, 103994678, 104301004, 117843310, 124489038, 124636988, 124801035, 125324613, 125352521, 126621128, 126653073, 126670260, 128971698, 131317931, 131813290
|
||||
Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [536327] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References | |||||
Ref 538508 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018550. | ||||
Ref 542149 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7141). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.