Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0IO0I
|
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| Former ID |
DNC008725
|
||||
| Drug Name |
Go-Y022
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H18O5
|
||||
| Canonical SMILES |
COC1=C(C=CC(=C1)C=CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
|
||||
| InChI |
1S/C19H18O5/c1-23-18-11-13(5-9-16(18)21)3-7-15(20)8-4-14-6-10-17(22)19(12-14)24-2/h3-12,21-22H,1-2H3/b7-3+,8-4+
|
||||
| InChIKey |
ISIMGBQRFXXNON-FCXRPNKRSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 2D6 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Metabolism of xenobiotics by cytochrome P450 | ||||
| Drug metabolism - cytochrome P450 | |||||
| Serotonergic synapse | |||||
| Reactome | Xenobiotics | ||||
| WikiPathways | Metapathway biotransformation | ||||
| Tamoxifen metabolism | |||||
| Oxidation by Cytochrome P450 | |||||
| Vitamin D Receptor Pathway | |||||
| Aripiprazole Metabolic Pathway | |||||
| Fatty Acid Omega Oxidation | |||||
| Codeine and Morphine Metabolism | |||||
| References | |||||
| REF 1 | Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues. | ||||
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