| Drug General Information |
| Drug ID |
D0IF0C
|
| Former ID |
DNC000819
|
| Drug Name |
Isoprenaline
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C11H17NO3
|
| InChI |
InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
|
| InChIKey |
JWZZKOKVBUJMES-UHFFFAOYSA-N
|
| CAS Number |
CAS 132-17-2
|
| PubChem Compound ID |
|
| PubChem Substance ID |
9268, 75322, 91788, 611308, 3133594, 5272313, 8152391, 10535368, 11336069, 11361308, 11363843, 11366405, 11368967, 11371528, 11373566, 11377129, 11462280, 11467125, 11468245, 11484778, 11486793, 11488877, 11490290, 11491839, 11494763, 11534308, 14748912, 24430805, 24715029, 26512260, 26752240, 29222898, 46507323, 47216837, 47291195, 47365254, 47440329, 47515375, 47810812, 47959817, 48334566, 48416134, 49892804, 49892806, 49892807, 50104946, 50111114, 53790889, 56313305, 56313643
|
| ChEBI ID |
ChEBI:6046
|
| SuperDrug ATC ID |
C01CA02; R03AB02; R03CB01
|
| SuperDrug CAS ID |
cas=007683592
|
| Target and Pathway |
| Target(s) |
Beta-1 adrenergic receptor |
Target Info |
Agonist |
[2]
|
|---|
| Beta-2 adrenergic receptor |
Target Info |
Agonist |
[2]
|
|
KEGG Pathway
|
Calcium signaling pathway
|
|
cGMP-PKG signaling pathway
|
|
cAMP signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Endocytosis
|
|
Adrenergic signaling in cardiomyocytes
|
|
Gap junction
|
|
Salivary secretion
|
|
Dilated cardiomyopathyhsa04020:Calcium signaling pathway
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
Beta1 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
Beta2 adrenergic receptor signaling pathway
|
|
Pathway Interaction Database
|
Arf6 trafficking events
|
|
Arf6 signaling events
|
|
PathWhiz Pathway
|
Muscle/Heart Contraction
|
|
Reactome
|
Adrenoceptors
|
|
G alpha (s) signalling eventsR-HSA-390696:Adrenoceptors
|
|
G alpha (s) signalling events
|
|
WikiPathways
|
Monoamine GPCRs
|
|
Calcium Regulation in the Cardiac Cell
|
|
GPCRs, Class A Rhodopsin-like
|
|
Endothelin Pathways
|
|
GPCR ligand binding
|
|
GPCR downstream signalingWP58:Monoamine GPCRs
|
|
Vitamin D Receptor Pathway
|
|
GPCR downstream signaling
|
|
GPCRs, Other
|
| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 536). |
|---|
| REF 2 | Current therapeutic uses and potential of beta-adrenoceptor agonists and antagonists. Eur J Clin Pharmacol. 1998 Feb;53(6):389-404. |
|---|
