| Drug General Information |
| Drug ID |
D0GV9Q
|
| Former ID |
DNC002603
|
| Drug Name |
N-Formylmethionine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C6H11NO3S
|
| Canonical SMILES |
CSCCC(C(=O)O)NC=O
|
| InChI |
1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
|
| InChIKey |
PYUSHNKNPOHWEZ-YFKPBYRVSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
6033, 10298452, 16532964, 36883922, 46505840, 49742586, 57403163, 76191993, 85239783, 85244536, 87569918, 92297514, 104621308, 118314016, 128987974, 134932038, 137007330, 138672551, 144220628, 160797390, 160967478, 162528723, 163410064, 163632921, 164831445, 172860544, 185995338, 198977122, 204363658, 204938103, 219400602, 223535772, 223940100, 226424107, 241085784, 246681219, 249855625, 249926568, 250214585, 252070628, 252142044, 252314189, 252412016, 252547013
|
| Target and Pathway |
| Target(s) |
Glutamate--cysteine ligase regulatorysubunit |
Target Info |
Inhibitor |
[1]
|
|---|
| Antithrombin-III |
Target Info |
Inhibitor |
[1]
|
| NADH dehydrogenase |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Glutathione metabolism
|
|
Metabolic pathwayshsa04610:Complement and coagulation cascadeshsa00190:Oxidative phosphorylation
|
|
Metabolic pathways
|
|
Parkinson's disease
|
|
PANTHER Pathway
|
Blood coagulation
|
|
Pathway Interaction Database
|
Glypican 1 network
|
|
PathWhiz Pathway
|
Glutamate Metabolism
|
|
Glutathione Metabolism
|
|
Cysteine Metabolism
|
|
Reactome
|
Intrinsic Pathway of Fibrin Clot Formation
|
|
Common Pathway of Fibrin Clot Formation
|
|
WikiPathways
|
Transcriptional activation by NRF2
|
|
NRF2 pathway
|
|
Nuclear Receptors Meta-Pathway
|
|
Metabolism of amino acids and derivatives
|
|
Trans-sulfuration and one carbon metabolism
|
|
Trans-sulfuration pathway
|
|
Phase II conjugation
|
|
Glutathione metabolismWP558:Complement and Coagulation Cascades
|
|
Formation of Fibrin Clot (Clotting Cascade)WP623:Oxidative phosphorylation
|
|
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
|
|
Electron Transport Chain
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
